Human Gut Microbiota

Have you heard about the food additive E415? It is also known as xanthan gum. Most likely, you eat it several times a week. Xanthan gum is used in everyday foods such as baked goods, ice cream and salad dressings. The additive is also widely used as a substitute for gluten in gluten-free foods.

New research now shows that xanthan gum affects our gut microbiota.

The study was recently published in Nature Microbiology by a team of scientists at NMBU in collaboration with the University of Michigan and several other international partners.

"We were surprised at how much the human gut bacteria have adapted to this additive since it was introduced into the modern diet only fifty years ago," says NMBU researcher Sabina Leanti La Rosa (above).

When it was first introduced, xanthan gum was thought to not affect us as it was not digested by the human body. However, the new study shows that the additive nevertheless affects the bacteria that live in our intestines. And these bacteria are important for our health and well-being.

"The gut bacteria we have investigated show genetic changes and a rapid adaptation to enable them to digest this particular additive," explains professor Phil Pope.

He leads the Microbial Ecology and Meta-Omics group at NMBU, where the researchers who conducted the new study work.  READ MORE...