Missing Law of Evolution

A new “law of increasing functional information” reveals that complex natural systems, beyond just life on Earth, evolve towards higher complexity. This discovery expands traditional evolutionary theory, offering insights from cosmology to astrobiology.

Evolution of plants, animals: “A very special case within a far larger natural phenomenon.” Similar marvels occur with stars, planets, minerals, other complex systems; When a novel configuration works well and function improves, evolution occurs.

A paper in the prestigious Proceedings of the National Academy of Sciences today describes “a missing law of nature,” recognizing for the first time an important norm within the natural world’s workings.

In essence, the new law states that complex natural systems evolve to states of greater patterning, diversity, and complexity. In other words, evolution is not limited to life on Earth, it also occurs in other massively complex systems, from planets and stars to atoms, minerals, and more.  READ MORE...

Magnetic Fusion Plasma Machines

Florian Neukart, an Assistant Professor at the Leiden Institute, has proposed the Magnetic Fusion Plasma Drive (MFPD) as a novel space propulsion method. This concept combines fusion propulsion, ionic propulsion, and more, promising high energy density and fuel efficiency.




Florian Neukart introduces the Magnetic Fusion Plasma Drive, a revolutionary propulsion method combining fusion and ionic techniques. Offering immense energy density and numerous advantages, it could redefine space exploration, although challenges in sustaining fusion reactions in space remain.

Missions to the Moon, missions to Mars, robotic explorers to the outer Solar System, a mission to the nearest star, and maybe even a spacecraft to catch up to interstellar objects passing through our system. If you think this sounds like a description of the coming age of space exploration, then you’d be correct! 

At this moment, there are multiple plans and proposals for missions that will send astronauts and/or probes to all of these destinations to conduct some of the most lucrative scientific research ever performed. Naturally, these mission profiles raise all kinds of challenges, not the least of which is propulsion.


Simply put, humanity is reaching the limits of what conventional (chemical) propulsion can do. To send missions to Mars and other deep space destinations, advanced propulsion technologies are required that offer high acceleration (delta-v), specific impulse (Isp), and fuel efficiency. 

In a recent paper, Leiden Professor Florian Neukart proposes how future missions could rely on a novel propulsion concept known as the Magnetic Fusion Plasma Drive (MFPD). This device combines aspects of different propulsion methods to create a system that offers high energy density and fuel efficiency significantly greater than conventional methods.   READ MORE...

The Giant Magellan Telescope

Artist’s concept of the completed Giant Magellan Telescope. The Giant Magellan Telescope is finalizing its last primary mirror, with the goal to surpass current space telescopes in sensitivity and resolution. Leveraging U.S. manufacturing, it promises unparalleled astronomical insights and aims for operation by the decade’s end. Credit: GMTO Corporation






Seven of the world’s largest mirrors will search the Universe for life beyond Earth

The Giant Magellan Telescope begins the four-year process to fabricate and polish its seventh and final primary mirror, the last required to complete the telescope’s 368 square meter (3,961 square foot) light collecting surface, the world’s largest and most challenging optics ever produced. 

Together, the mirrors will collect more light than any other telescope in existence, allowing humanity to unlock the secrets of the Universe by providing detailed chemical analyses of celestial objects and their origin.

Last week, the University of Arizona Richard F. Caris Mirror Lab closed the lid on nearly 20 tons of the purest optical glass inside a one-of-a-kind oven housed beneath the stands of the Arizona Wildcats Football Stadium. 

The spinning oven will heat the glass to 1,165°C (2,129°F) so as it melts, it is forced outward to form the mirror’s curved paraboloid surface. Measuring 8.4 meters (26.7 feet) in diameter—about two stories tall when standing on edge—the mirror will cool over the next three months before moving into the polishing stage.  READ MORE...

Inbreeding Can Be Beneficial

The Svalbard reindeer, despite significant inbreeding and low genetic diversity, boasts a robust population of over 20,000, having adapted to Arctic conditions with unique traits like smaller size and the ability to digest mosses. Although they have evolved rapidly to past environmental changes, scientists fear the pace of current global warming may outstrip their capacity to adapt, posing a serious threat to their survival.



Reindeer have endured for over 7,000 years on the Arctic archipelago of Svalbard. Will they be able to withstand climate change?


Despite the challenges of inbreeding and limited genetic diversity, the Svalbard reindeer have remarkably adapted to harsh living conditions in an extraordinarily short period, a situation researchers term a genetic paradox. However, the question remains: can they withstand the impacts of climate change?


“Of all the subspecies of reindeer found in the high north, the Svalbard reindeer has the most inbreeding and the lowest genetic diversity,” says Nicolas Dussex, a postdoc at the Norwegian University of Science and Technology’s (NTNU) Department of Natural History.


It was only 7000-8000 years ago that the first reindeer migrated to Svalbard, most likely from Russia via Novaya Zemlya and the islands of Franz Josef Land. Perhaps there were no more than a few animals that established themselves on the Arctic archipelago. Evolutionary theory suggests this is a poor starting point since inbreeding can quickly lead to an accumulation of harmful mutations and genetic variants followed by disease and death.


But this has not prevented the Svalbard reindeer from evolving into what is today a viable population of more than 20,000 animals.

“Despite the low genetic diversity, they have managed to develop a number of adaptations to life in the High Arctic. They are, for example, smaller in size and have shorter legs than other northern reindeer and caribou subspecies,” says Dussex.

The ability to digest mosses in the absence of lichens, and to adjust their circadian rhythm to the extreme seasonal variations on Svalbard, are also traits the Svalbard reindeer have developed over the relatively short time they have lived isolated on the archipelago. 

Now, researchers at NTNU and collaborating institutions have analyzed genetic samples from 91 reindeer to see how they differ from their relatives on the mainland.  READ MORE...

Boosting Quantum Devices

MIT physicists, inspired by noise-canceling headphones, have advanced the coherence time of quantum bits by 20-fold, marking significant progress for quantum computing. The team used an “unbalanced echo” technique to counteract system noise, and they believe further improvements are possible. This breakthrough has vast potential, from quantum sensors in biology to advancements in quantum memory.



MIT researchers develop a protocol to extend the life of quantum coherence.

For years, researchers have tried various ways to coax quantum bits — or qubits, the basic building blocks of quantum computers — to remain in their quantum state for ever-longer times, a key step in creating devices like quantum sensors, gyroscopes, and memories.

A team of physicists from MIT have taken an important step forward in that quest, and to do it, they borrowed a concept from an unlikely source — noise-canceling headphones.


Led by Ju Li, the Battelle Energy Alliance Professor in Nuclear Engineering and professor of materials science and engineering, and Paola Cappellaro, the Ford Professor of Engineering in the Department of Nuclear Science and Engineering and Research Laboratory of Electronics, and a professor of physics, the team described a method to achieve a 20-fold increase in the coherence times for nuclear-spin qubits. 

The work is described in a paper published in Physical Review Letters. The first author of the study is Guoqing Wang PhD ’23, a recent doctoral student in Cappellaro’s lab who is now a postdoc at MIT.


“This is one of the main problems in quantum information,” Li says. “Nuclear spin (ensembles) are very attractive platforms for quantum sensors, gyroscopes, and quantum memory, (but) they have coherence times on the order of 150 microseconds in the presence of electronic spins … and then the information just disappears. 

What we have shown is that, if we can understand the interactions, or the noise, in these systems, we can actually do much better.”  READ MORE...

New Way to Measure Dark Energy

Researchers have discovered a method to potentially detect and measure dark energy by examining the motion between the Milky Way and Andromeda galaxies. This technique, still in its early stages, can estimate the upper value of the cosmological constant, a simple model of dark energy, which is five times higher than values determined from the early universe.




Researchers from the University of Cambridge have discovered a new way to measure dark energy – the mysterious force that makes up more than two-thirds of the universe and is responsible for its accelerating expansion – in our own cosmic backyard.

The researchers found that it may be possible to detect and measure dark energy by studying Andromeda, our galactic next-door neighbor that is on a slow-motion collision course with the Milky Way.


Since it was first identified in the late 1990s, scientists have used very distant galaxies to study dark energy but have yet to directly detect it. 

However, the Cambridge researchers found that by studying how Andromeda and the Milky Way are moving toward each other given their collective mass, they could place an upper limit on the value of the cosmological constant, which is the simplest model of dark energy. 

The upper limit they found is five times higher than the value of the cosmological constant that can be detected from the early universe.

Although the technique is still early in its development, the researchers say that it could be possible to detect dark energy by studying our own cosmic neighborhood. The results are reported in The Astrophysical Journal Letters.

Everything we can see in our world and in the skies – from tiny insects to massive galaxies – makes up just five percent of the observable universe. 

The rest is dark: scientists believe that about 27% of the universe is made of dark matter, which holds objects together, while 68% is dark energy, which pushes objects apart.  READ MORE...

Neutrinos and Dark Matter

PNNL chemist Isaac Arnquist examines ultra-low radiation copper cables specially created for sensitive physics detection experiments. Credit: Andrea Starr, Pacific Northwest National Laboratory



Ultra-low radiation cables reduce background noise for neutrino and dark matter detectors.

Imagine trying to tune a radio to a single station but instead encountering static noise and interfering signals from your own equipment. That is the challenge facing research teams searching for evidence of extremely rare events that could help understand the origin and nature of matter in the universe. 

It turns out that when you are trying to tune into some of the universe’s weakest signals, it helps to make your instruments very quiet.

Around the world, more than a dozen teams are listening for the pops and electronic sizzle that might mean they have finally tuned into the right channel. These scientists and engineers have gone to extraordinary lengths to shield their experiments from false signals created by cosmic radiation. 

Most such experiments are found in very inaccessible places—such as a mile underground in a nickel mine in Sudbury, Ontario, Canada, or in an abandoned gold mine in Lead, South Dakota—to shield them from naturally radioactive elements on Earth. 

However, one such source of fake signals comes from natural radioactivity in the very electronics that are designed to record potential signals.

Ultra-low radiation cables reduce background noise for neutrino and dark matter detectors.

Imagine trying to tune a radio to a single station but instead encountering static noise and interfering signals from your own equipment. That is the challenge facing research teams searching for evidence of extremely rare events that could help understand the origin and nature of matter in the universe. 

It turns out that when you are trying to tune into some of the universe’s weakest signals, it helps to make your instruments very quiet.

Around the world, more than a dozen teams are listening for the pops and electronic sizzle that might mean they have finally tuned into the right channel. These scientists and engineers have gone to extraordinary lengths to shield their experiments from false signals created by cosmic radiation. 

Most such experiments are found in very inaccessible places—such as a mile underground in a nickel mine in Sudbury, Ontario, Canada, or in an abandoned gold mine in Lead, South Dakota—to shield them from naturally radioactive elements on Earth. 

However, one such source of fake signals comes from natural radioactivity in the very electronics that are designed to record potential signals.  READ MORE...

Smallest Known Way to Guide Light

Scientists at the University of Chicago found a glass crystal just a few atoms thick can trap and carry light—and could be used for applications. The material is visible as the thin line in the center of the plastic, held by study co-author Hanyu Hong. Credit: Jean Lachat



2D optical waveguides could pave the way for innovative technology.

Channeling light from one location to another is the backbone of our modern world. Across deep oceans and vast continents, fiber optic cables transport light containing data ranging from YouTube clips to banking transmissions—all within fibers as thin as a strand of hair.

University of Chicago Prof. Jiwoong Park, however, wondered what would happen if you made even thinner and flatter strands—in effect, so thin that they’re actually 2D instead of 3D. What would happen to the light?

Through a series of innovative experiments, he and his team found that a sheet of glass crystal just a few atoms thick could trap and carry light. Not only that, but it was surprisingly efficient and could travel relatively long distances—up to a centimeter, which is very far in the world of light-based computing.

The research, recently published in the journal Science, demonstrates what are essentially 2D photonic circuits, and could open paths to new technology.

“We were utterly surprised by how powerful this super-thin crystal is; not only can it hold energy, but deliver it a thousand times further than anyone has seen in similar systems,” said lead study author Jiwoong Park, a professor and chair of chemistry and faculty member of the James Franck Institute and Pritzker School of Molecular Engineering. “The trapped light also behaved like it is traveling in a 2D space.”

Guiding light
The newly invented system is a way to guide light—known as a waveguide—that is essentially two-dimensional. In tests, the researchers found they could use extremely tiny prisms, lenses, and switches to guide the path of the light along a chip—all the ingredients for circuits and computations.  READ MORE...

World's Most Powerful X-ray Laser

The newly upgraded Linac Coherent Light Source (LCLS) X-ray free-electron laser (XFEL) at the Department of Energy’s SLAC National Accelerator Laboratory successfully produced its first X-rays. The upgrade, called LCLS-II, creates unparalleled capabilities that will usher in a new era in research with X-rays. Credit: Greg Stewart/SLAC National Accelerator Laboratory




With up to a million X-ray flashes per second, 8,000 times more than its predecessor, it transforms the ability of scientists to explore atomic-scale, ultrafast phenomena that are key to a broad range of applications, from quantum materials to clean energy technologies and medicine.

The newly upgraded Linac Coherent Light Source (LCLS) X-ray free-electron laser (XFEL) at the Department of Energy’s SLAC National Accelerator Laboratory successfully produced its first X-rays, and scientists around the world are already lined up to kick off an ambitious science program.

The upgrade, called LCLS-II, creates unparalleled capabilities that will usher in a new era in research with X-rays. 

Scientists will be able to examine the details of quantum materials with unprecedented resolution to drive new forms of computing and communications; reveal unpredictable and fleeting chemical events to teach us how to create more sustainable industries and clean energy technologies; study how biological molecules carry out life’s functions to develop new types of pharmaceuticals; and study the world on the fastest timescales to open up entirely new fields of scientific investigation.

“This achievement marks the culmination of over a decade of work,” said LCLS-II Project Director Greg Hays. “It shows that all the different elements of LCLS-II are working in harmony to produce X-ray laser light in an entirely new mode of operation.”  READ MORE...

Energy-Efficient Spintronics Computing

Spintronics is a promising approach to computer technology that uses the intrinsic angular momentum of electrons to process information, potentially making computers faster and more energy-efficient. Researchers have been experimenting with magnetic whirls, or skyrmions, and recently enhanced their diffusion rate by tenfold using synthetic antiferromagnets, paving the way for efficient spin-based computing.




Researchers in Germany and Japan have been able to increase the diffusion of magnetic whirls, so-called skyrmions, by a factor of ten.

In today’s world, our lives are unimaginable without computers. Up until now, these devices process information using primarily electrons as charge carriers, with the components themselves heating up significantly in the process. Active cooling is thus necessary, which comes with high energy costs. 

Spintronics aims to solve this problem: Instead of utilizing the electron flow for information processing, it relies on their spin or their intrinsic angular momentum. This approach is expected to have a positive impact on the size, speed, and sustainability of computers or specific components.

Magnetic Whirls Store and Process Information
Science often does not simply consider the spin of an individual electron, but rather magnetic whirls composed of numerous spins. These whirls called skyrmions emerge in magnetic metallic thin layers and can be considered as two-dimensional quasi-particles. 

On the one hand, the whirls can be deliberately moved by applying a small electric current to the thin layers; on the other hand, they move randomly and extremely efficiently due to diffusion. 

The feasibility of creating a functional computer based on skyrmions was demonstrated by a team of researchers from Johannes Gutenberg University Mainz (JGU), led by Professor Dr. Mathias Kläui, using an initial prototype. This prototype consisted of thin, stacked metallic layers, some only a few atomic layers thick.  READ MORE...

Tougher Than Kevlar

Numerous scientists aspire to unlock the remarkable capability of spiders to spin silk threads that are immensely strong, lightweight, and flexible. In fact, pound for pound, spider silk is stronger than steel and tougher than Kevlar. However, no one has been able to replicate the spiders’ work yet.

If we ever manage to develop a synthetic equivalent with these characteristics, a whole new world of possibilities may open: Artificial spider silk could replace materials like Kevlar, polyester, and carbon fiber in industries and be used, for example, to make lightweight and flexible bulletproof vests.

Postdoc and biophysicist Irina Iachina from the Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), is involved in this race to uncover the recipe for super silk.

She has been fascinated by spider silk since her time as a master’s student at SDU, and currently, she is researching the topic at the Massachusetts Institute of Technology in Boston with support from the Villum Foundation.

As part of her research, she is collaborating with associate professor and biophysicist Jonathan Brewer at SDU, who is an expert in using various types of microscopes to peer into biological structures.

Together, they have now, for the first time, studied the internal parts of spider silk using an optical microscope without cutting or opening the silk in any way. This work has now been published in the journals Scientific Reports and Scanning.

“We have used several advanced microscopy techniques, and we have also developed a new kind of optical microscope that allows us to look all the way into a piece of fiber and see what’s inside,” explains Jonathan Brewer.  READ MORE...

Secret Role in Origin of Life

Researchers have developed a new method to observe chemical reactions in liquids, shedding light on reactions involving molecules like urea that may have contributed to the emergence of life on Earth. The technique involves a special apparatus that produces a fine liquid jet and X-ray spectroscopy, allowing scientists to study reactions taking place in mere femtoseconds.




Scientists from ETH Zurich and the University of Geneva have developed a new technique that allows them to observe chemical reactions taking place in liquids at extremely high temporal resolution. This innovation enables them to track how molecules change within in mere femtoseconds – in other words, within a few quadrillionths of a second.

This breakthrough builds upon prior research by the same team, led by Hans Jakob Wörner, Professor of Physical Chemistry at ETH Zurich. That work yielded similar results for reactions that take place in gas environments.

To expand their X-ray spectroscopy observations to liquids, the researchers had to design an apparatus capable of producing a liquid jet with a diameter of less than one micrometer in a vacuum. This was essential because if the jet were any wider, it would absorb some of the X-rays used to measure it.

Molecular pioneer in biochemistry
Using the new method, the researchers were able to gain insights into the processes that led to the emergence of life on Earth. Many scientists assume that urea played a pivotal role here. It is one of the simplest molecules containing both carbon and nitrogen.

What’s more, it’s highly likely that urea was present even when the Earth was very young, something that was also suggested by a famous experiment done in the 1950s: American scientist Stanley Miller concocted a mixture of those gases believed to have made up the planet’s primordial atmosphere and exposed it to the conditions of a thunderstorm. This produced a series of molecules, one of which was urea.  READ MORE...

Eradicating Plaques and Cavities

Scientists have discovered that the molecule DIM reduces biofilms causing dental plaque by 90%. Its addition to toothpaste and mouthwash could revolutionize dental hygiene.

3,3′-Diindolylmethane (DIM) decreased the Streptococcus mutans biofilm, a leading contributor to plaque and cavities, by 90%.

A significant portion of the global population experiences persistent issues with dental plaque and cavities or will face them at some time. While toothpaste, mouthwash, and routine dental visits help in prevention, there’s always room for improvement.

Researchers from Ben-Gurion University of the Negev, in collaboration with teams from Sichuan University and the National University of Singapore, have identified that 3,3′-Diindolylmethane (DIM) – a naturally occurring molecule also referred to as bisindole – can reduce biofilms responsible for plaque and cavities by a remarkable 90%.

The molecule is also found to have anti-carcinogenic properties.  Their findings were recently published in the journal Antibiotics.

Your mouth is a great reservoir for bacteria such as S. mutans, which is believed to be one of the primary actors in dental cavities. S. mutans grows in the moist and sugary atmosphere of your mouth after food in a biofilm that coats your teeth. 

Biofilm generates plaque, attacks enamel, and causes cavities. The scientists found that the bisindole (DIM) disrupted that biofilm by 90% and therefore the bacterium was not given a chance to grow.  READ MORE...

Quantum Systems Defy Freezing Logic

Researchers investigated the Mpemba effect in quantum systems, a phenomenon where hotter water can freeze faster than cooler water. This quantum Mpemba effect retains memory of its initial conditions, affecting its thermal relaxation later. The team used two systems with quantum dots and discovered the thermal quantum Mpemba effect across various conditions, suggesting possible broader applications beyond thermal analysis.



Hotter quantum systems can cool faster than initially colder equivalents.

Does hot water freeze faster than cold water? Aristotle may have been the first to tackle this question that later became known as the Mpemba effect.

This phenomenon originally referred to the non-monotonic initial temperature dependence of the freezing start time, but it has been observed in various systems — including colloids — and has also become known as a mysterious relaxation phenomenon that depends on initial conditions.

What Is the Mpemba Effect?
The Mpemba effect is a counterintuitive phenomenon where hot water can freeze faster than cold water under certain conditions. Named after Erasto Mpemba, a Tanzanian student who observed this effect in the 1960s and subsequently brought it to the attention of the scientific community, the phenomenon has been a topic of curiosity for centuries, with references dating back to the likes of Aristotle. The exact cause of the Mpemba effect is still a topic of debate among scientists.

Recent Findings
Now, a team of researchers from Kyoto University and the Tokyo University of Agriculture and Technology has shown that the temperature quantum Mpemba effect can be realized over a wide range of initial conditions.

“The quantum Mpemba effect bears the memory of initial conditions that result in anomalous thermal relaxation at later times,” explains project leader and co-author Hisao Hayakawa at KyotoU’s Yukawa Institute for Theoretical Physics.  READ MORE...

Remnant Galaxies from Universe's Inception

The red region (left) shows the shell enclosed by the Baryon Acoustic Oscillation, with individual galaxies depicted as luminous tiny specks. The blue filaments show the greater Cosmic Web, with previously known features like Laniākea highlighted. Credit: Frédéric Durillon, Animea Studio; Daniel Pomarède, IRFU, CEA University Paris-Saclay. This work benefited from a government funding by France 2030 (P2I – Graduate School of Physics) under reference ANR-11-IDEX-0003



Astronomers have identified an immense bubble, Hoʻoleilana, 820 million light years away. This structure, believed to be a remnant from the universe’s inception and larger than predicted, offers valuable insights into galaxy evolution and the universe’s expansion dynamics.


A University of Hawaiʻi-led discovery of an immense bubble 820 million light years from Earth is believed to be a fossil-like remnant of the birth of the universe. Astronomer Brent Tully from the UH Institute for Astronomy and his team unexpectedly found the bubble within a web of galaxies. The entity has been given the name Hoʻoleilana, a term drawn from the Kumulipo, a Hawaiian creation chant evoking the origin of structure.


The new findings published on September 5 in The Astrophysical Journal, mention these massive structures are predicted by the Big Bang theory, as the result of 3D ripples found in the material of the early universe, known as Baryon Acoustic Oscillations (BAO).

The Unexpected Find
“We were not looking for it. It is so huge that it spills to the edges of the sector of the sky that we were analyzing,” explained Tully. “As an enhancement in the density of galaxies, it is a much stronger feature than expected. 

The very large diameter of one billion light years is beyond theoretical expectations. If its formation and evolution are in accordance with theory, this BAO is closer than anticipated, implying a high value for the expansion rate of the universe.”

Astronomers located the bubble using data from Cosmicflows-4, which is to date, the largest compilation of precise distances to galaxies. Tully co-published the exceptional catalog in the fall of 2022. 

His team of researchers believe this may be the first time astronomers identified an individual structure associated with a BAO. The discovery could help bolster scientists’ knowledge of the effects of galaxy evolution.     READ MORE...

Quantum Squeezing

Lee McCuller, a physics professor and quantum squeezing expert, is developing innovative techniques to enhance the sensitivity of LIGO, the world’s most advanced gravitational wave detector. His future ambition is to broaden the application of these techniques beyond LIGO.



New Caltech professor Lee McCuller is making quantum measurements even more precise.

From a young age, new Assistant Professor of Physics, Lee McCuller, enjoyed the hands-on process of building things. This interest was fostered by his uncle, who created a power supply for him. McCuller used this in conjunction with electronic hobby kits from RadioShack, performing simple tasks such as operating analog circuits to switch lights and motors on and off. 

Today, McCuller’s engineering prowess is applied to an exceptionally advanced device, what some would call the most advanced measurement device in the world: the Laser Interferometer Gravitational-wave Observatory, or LIGO.


McCuller is a recognized expert in a field known as quantum squeezing, a technique utilized at LIGO to achieve extremely precise measurements of gravitational waves. that travel millions and billions of light-years across space to reach us. When black holes and collapsed stars, called neutron stars, collide, they generate ripples in space-time, or gravitational waves. 

LIGO’s detectors—located in Washington and Louisiana—specialize in picking up these waves but are limited by quantum noise, an inherent property of quantum mechanics that results in photons popping in and out of existence in empty space. Quantum squeezing is a complex method for reducing this unwanted noise.  READ MORE...

Extending Human Longevity VIA the Longevity Gene

Researchers successfully transferred a longevity gene from naked mole rats to mice, leading to enhanced health and increased lifespan. Naked mole rats, noted for their resistance to age-related diseases, have a gene that produces high molecular weight hyaluronic acid (HMW-HA), which when introduced to mice, demonstrated potential anti-aging benefits.






The successful transfer of a gene that produces HMW-HA paves the way for improving the health and lifespan of humans, too.

In a groundbreaking endeavor, scientists at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, leading to enhanced health and a longer lifespan for the mice.

Naked mole rats, known for their long lifespans and exceptional resistance to age-related diseases, have long captured the attention of the scientific community. By introducing a specific gene responsible for enhanced cellular repair and protection into mice, the Rochester researchers have opened exciting possibilities for unlocking the secrets of aging and extending human lifespan.

“Our study provides a proof of principle that unique longevity mechanisms that evolved in long-lived mammalian species can be exported to improve the lifespans of other mammals,” says Vera Gorbunova, the Doris Johns Cherry Professor of biology and medicine at Rochester.

Gorbunova, along with Andrei Seluanov, a professor of biology, and their colleagues, report in a study published in Nature that they successfully transferred a gene responsible for making high molecular weight hyaluronic acid (HMW-HA) from a naked mole rat to mice. This led to improved health and an approximate 4.4 percent increase in the median lifespan for the mice.

A unique mechanism for cancer resistance
Naked mole rats are mouse-sized rodents that have exceptional longevity for rodents of their size; they can live up to 41 years, nearly ten times as long as similar-sized rodents. Unlike many other species, naked mole rats do not often contract diseases—including neurodegeneration, cardiovascular disease, arthritis, and cancer—as they age. Gorbunova and Seluanov have devoted decades of research to understanding the unique mechanisms that naked mole rats use to protect themselves against aging and diseases.     READ MORE...

Neuroscience Breakthrough

See-through 3D model that shows the axon (red), medium spinal motor neuron (green), and astrocyte converging at the synapse (yellow). Credit: Center for Translational Neuromedicine, University of Rochester and University of Copenhagen





Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer-scale models will help scientists better understand and study neurodegenerative diseases such as Huntington’s disease and schizophrenia.

The new study appears in the journal PNAS and was authored by a team led by Steve Goldman, MD, Ph.D., co-director of the Center for Translational Neuromedicine at the University of Rochester and the University of Copenhagen. The findings represent a significant technical achievement that allows researchers to study the different cells that converge at individual synapses at a level of detail not previously achievable.

“It is one thing to understand the structure of the synapse from the literature, but it is another to see the precise geometry of interactions between individual cells with your own eyes,” said Abdellatif Benraiss, Ph.D., a research associate professor in the Center for Translational Neuromedicine and co-author of the study. “The ability to measure these extremely small environments is a young field, and holds the potential to advance our understanding of a number of neurodegenerative and neuropsychiatric diseases in which synaptic function is disturbed.”

The researchers used the new technique to compare the brains of healthy mice to mice carrying the mutant gene that causes Huntington’s disease. Prior research in Goldman’s lab has shown that dysfunctional astrocytes play a key role in the disease. Astrocytes are members of a family of support cells in the brain called glia and help maintain the proper chemical environment at the synapse.

The researchers focused on synapses that involve medium spiny motor neurons, the progressive loss of these cells is a hallmark of Huntington’s disease. The researchers first had to identify synapses hidden within the tangle of the three different cells that converge at the site: the pre-synaptic axon from a distant neuron; its target, the post-synaptic medium spiny motor neuron; and the fiber processes of a neighboring astrocyte.   READ MORE...

Vibrations Prevent Quantum Computing Loses

Michigan State University researchers have discovered how to utilize vibrations, usually an obstacle in quantum computing, as a tool to stabilize quantum states. Their research provides insights into controlling environmental factors in quantum systems and has implications for the advancement of quantum technology.



When quantum systems, such as those used in quantum computers, operate in the real world, they can lose information to mechanical vibrations.

New research led by Michigan State University, however, shows that a better understanding of the coupling between the quantum system and these vibrations can be used to mitigate loss.

The research, published in the journal Nature Communications, could help improve the design of quantum computers that companies such as IBM and Google are currently developing.

The Challenge of Isolation in Quantum Computing
Nothing exists in a vacuum, but physicists often wish this weren’t the case. Because if the systems that scientists study could be completely isolated from the outside world, things would be a lot easier.

Take quantum computing. It’s a field that’s already drawing billions of dollars in support from tech investors and industry heavyweights including IBM, Google, and Microsoft. But if the tiniest vibrations creep in from the outside world, they can cause a quantum system to lose information.

For instance, even light can cause information leaks if it has enough energy to jiggle the atoms within a quantum processor chip.

The Problem of Vibrations
“Everyone is really excited about building quantum computers to answer really hard and important questions,” said Joe Kitzman, a doctoral student at Michigan State University. “But vibrational excitations can really mess up a quantum processor.”

However, with new research published in the journal Nature Communications, Kitzman and his colleagues are showing that these vibrations need not be a hindrance. In fact, they could benefit quantum technology.     READ MORE...

Six Degrees of Separation

Researchers have mathematically explained the “six degrees of separation” phenomenon, indicating that individuals in a network aim for strategic connections, balancing costs and benefits of these ties. The original experiment by Stanley Milgram in 1967 showed that in the vast American society, it took only around six connections to link two random people, a finding that has since been reaffirmed through various studies.




Researchers from Bar-Ilan University prove there are just six degrees of separation in a social network.

Do you know someone who knows someone? We’ve all delved into this thought experiment, marveling at the idea that in the vast web of humanity, random people can be linked through very small chains of acquaintances — typically, around six. 

Recently, a group of researchers from across the globe discovered that this magic of six degrees can be explained mathematically. The intriguing phenomenon, they show, is linked to another social experience we all know too well — the struggle of cost vs. benefit in establishing new social ties.

In 1967, a farmer in Omaha, Nebraska received a peculiar letter in his mailbox. The sender was Prof. Stanley Milgram, of Harvard University, and the intended recipient was one of his peers. “If you happen to know this person,” the message read, “please forward this letter to him.”


Of course, the chances of such a direct acquaintance across such a vast social and geographical distance – from Boston to Omaha — were extremely slim, and therefore, the letter further requested that if the recipient didn’t know the intended addressee, they should forward the letter to someone who might.


This letter was one of about 300 identical packages sent with similar instructions. The 300 independent letters began circulating across the United States in pursuit of a social pathway linking “Joe” from the farmlands of middle America with the academic hub of the East Coast. 

Not all letters made it through, but the ones that did recorded, for the first time experimentally, the familiar social paths – a friend of a friend of a friend – that connect American society.

Quite surprisingly, the paths were found to be extremely short. In a society of hundreds of millions of individuals, the experiment found that it only takes about six handshakes to bridge between two random people. Indeed, Milgram’s experiment confirmed what many of us sense intuitively, that we live in a small world, divided by a mere six degrees of separation.  READ MORE...