Friday, July 23
Harris Losing Fans
Tucked at the end of the results are favorability ratings for various political figures, including the vice president.
The poll was conducted July 16-18, with a sample size of 1,997 registered voters and a margin of error of plus or minus 2 percentage points.
Just 45 percent of respondents have a favorable view of Harris, compared to 47 percent who have an unfavorable view.
More men, at 48 percent, have a favorable view of Harris, compared to the 47 percent who have an unfavorable view. Women, however, are not fans of the vice president, with 43 percent having a favorable view, compared to the 47 percent who have an unfavorable view.
So few Republican women, at 3 percent, have a favorable view of Harris, that it’s possible that with the margin of error that the Vice President has virtually no support from the demographic.
Republican women have a more favorable rating of President Joe Biden, at 9 percent.
Those demographics which have equally or even more significant non-support for Harris include the 2 percent favorable ratings from those who strongly disapprove of the job Biden is doing and the 1 percent who have a very unfavorable view of Biden.
The vice president has most of her support from Democrats and Liberals, at 85 percent each, as well as from 86 percent of Democratic women. Slightly more of respondents who voted for Hillary Clinton in 2016, at 85 percent, have a favorable view of her than the 82 percent of respondents who voted for Joe Biden in 2020. READ MORE
Adult Brains
(Image caption: A 3-D animated image showing our synapse phagocytosis reporter in mouse hippocampus. Presynapses in green, astrocytes in white, and microglia in blue. Phagocytosed presynapses by glia were shown in red.)
Astrocytes Eat Connections to Maintain Plasticity in Adult Brains
Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away. Adult brains undergo similar pruning, but it was unclear how or why synapses in the adult brain get eliminated.
Now, a team of KAIST researchers has found the mechanism underlying plasticity and, potentially, neurological disorders in adult brains. They published their findings in Nature.
“Our findings have profound implications for our understanding of how neural circuits change during learning and memory, as well as in diseases,” said paper author Won-Suk Chung, an assistant professor in the Department of Biological Sciences at KAIST. “Changes in synapse number have strong association with the prevalence of various neurological disorders, such as autism spectrum disorder, schizophrenia, frontotemporal dementia, and several forms of seizures.”
Gray matter in the brain contains microglia and astrocytes, two complementary cells that, among other things, support neurons and synapses. Microglial are a frontline immunity defense, responsible for eating pathogens and dead cells, and astrocytes are star-shaped cells that help structure the brain and maintain homeostasis by helping to control signaling between neurons. According to Professor Chung, it is generally thought that microglial eat synapses as part of its clean-up effort in a process known as phagocytosis.
“Using novel tools, we show that, for the first time, it is astrocytes and not microglia that constantly eliminate excessive and unnecessary adult excitatory synaptic connections in response to neuronal activity,” Professor Chung said. “Our paper challenges the general consensus in this field that microglia are the primary synapse phagocytes that control synapse numbers in the brain.”
Professor Chung and his team developed a molecular sensor to detect synapse elimination by glial cells and quantified how often and by which type of cell synapses were eliminated. They also deployed it in a mouse model without MEGF10, the gene that allows astrocytes to eliminate synapses. Adult animals with this defective astrocytic phagocytosis had unusually increased excitatory synapse numbers in the hippocampus. Through a collaboration with Dr. Hyungju Park at KBRI, they showed that these increased excitatory synapses are functionally impaired, which cause defective learning and memory formation in MEGF10 deleted animals.
“Through this process, we show that, at least in the adult hippocampal CA1 region, astrocytes are the major player in eliminating synapses, and this astrocytic function is essential for controlling synapse number and plasticity,” Chung said.
Professor Chung noted that researchers are only beginning to understand how synapse elimination affects maturation and homeostasis in the brain. In his group’s preliminary data in other brain regions, it appears that each region has different rates of synaptic elimination by astrocytes. They suspect a variety of internal and external factors are influencing how astrocytes modulate each regional circuit, and plan to elucidate these variables.
“Our long-term goal is understanding how astrocyte-mediated synapse turnover affects the initiation and progression of various neurological disorders,” Professor Chung said. “It is intriguing to postulate that modulating astrocytic phagocytosis to restore synaptic connectivity may be a novel strategy in treating various brain disorders.”
Past Life on Mars
The space agency's Curiosity rover made the surprising discovery while investigating clay-rich sedimentary rocks around its landing site in Gale Crater, a former lake that was made when an asteroid struck the Red Planet roughly 3.6 billion years ago.
Clay is a good signpost towards evidence of life because it's usually created when rocky minerals weather away and rot after contact with water — a key ingredient for life. It is also an excellent material for storing microbial fossils.
But when Curiosity took two samples of ancient mudstone, a sedimentary rock containing clay, from patches of the dried-out lake bed, dated to the same time and place (3.5 billion years ago and just 400m apart), researchers found that one patch contained only half the expected amount of clay minerals.
Instead, that patch held a greater quantity of iron oxides, the compounds that give Mars its rusty hue. TO READ MORE
China Rivaling Airbus and Boeing
he airline industry is dominated by European planes like the Airbus and the American-made Boeing, which are battling the aviation market against China’s aircraft manufacturer Comac. The company has been testing a new passenger jet called the C919 for short-haul flights, and the C929 for long-haul.
It’s all part of the Chinese government’s Made in China 2025 strategy, which aims to reduce China’s dependence on foreign technology.
“National airlines have long been a marker of a state’s status and prestige in the international sphere, so it’s not surprising to see a new airline in China as its importance and influence in global affairs grows,” said Michelle Murray, a professor and chair at the political studies program at Bard College in New York. TO READ MORE
“National airlines have long been a marker of a state’s status and prestige in the international sphere, so it’s not surprising to see a new airline in China as its importance and influence in global affairs grows,” said Michelle Murray, a professor and chair at the political studies program at Bard College in New York. TO READ MORE
Math & Black Holes
The proximity of each reflection is dependent on the angle of observation with respect to the black hole, and the rate of the black hole's spin, according to a mathematical solution worked out by physics student Albert Sneppen of the Niels Bohr Institute in Denmark.
This is really cool, absolutely, but it's not just really cool. It also potentially gives us a new tool for probing the gravitational environment around these extreme objects.
"There is something fantastically beautiful in now understanding why the images repeat themselves in such an elegant way," Sneppen said. "On top of that, it provides new opportunities to test our understanding of gravity and black holes."
If there's one thing that black holes are famous for, it's their extreme gravity. Specifically that, beyond a certain radius, the fastest achievable velocity in the Universe, that of light in a vacuum, is insufficient to achieve escape velocity.
That point of no return is the event horizon – defined by what's called the Schwarszchild radius – and it's the reason why we say that not even light can escape from a black hole's gravity. TO READ MORE
Fairytale Scandanavian Green Roofs
Scandinavians are serious about their green roofs. They’ve had them for a while now and it doesn’t look like they’re going anywhere. They even have a competition every year to determine the best green roof project in Scandinavia by the Scandinavian Green Roof Association! But there is a reason why Scandinavians like these green roofs so much… They are not only a beautiful feature for a house, but they also offer numerous social, environmental and financial benefits. They absorb rainwater, reduce winter heating costs, reduce summer air-conditioning costs, provide insulation, and are long lasting - just to name a few.
Thursday, July 22
Thursday Morning in East Tennessee
The Tennessee Valley is going to be experiencing 90 degree temperatures today and for the most part, I am going to be remaining inside.
I only watch FOX NEWS these days and it appears that the news is the SOS everyday... SOS is same ole shit...
- Defunding Police
- Critical Race Theory
- Eliminating Whiteness
- Black Lives Matter
- WOKE Awareness
- Illegal Immigration
I watch FOX News for about an hour or two and then I have had enough of all the bullshit that is going on...
I would like to have full employment
I would like to have a growing economy
I would like to have a strong military
I would like for the USA to be the global leader
I would like to end all wars
I would like to end all racism
I value my freedom of speech
As a decade+ long cancer survivor, I value life in all of its aspects... and, I realize that we will always need management even though most managers are ASSHOLES, arrogant, and egotisticals sons-of-bitches... I also realize that the wealthy must always be around regardless of our political system or type of government.
It is THE WEALTHY THAT FRIGGING PAY FOR EVERYTHING... and if we screw with them too much they will just move out of the USA... they can live anywhere... they will create a new USA no matter where they decide to live...
Sometimes, the general public is just plain STUPID...
Done Away With Cable TV
We both have cell phones so we no longer needed our landline through our cable provider.
We went from a cable coax connection to the internet to a fiber optic internet connect which is must faster and much more reliable and has greater bandwidth than cable internet.
We went from cable TV to HULU LIVE which includes much more than our current cable package and the fee is much less than what we were paying.
In short, we are getting more for less money each month.
We are streaming HULU through a ROKU device which is a one time equipment purchase. And, we have all of ROKU's free channels and movies as well.
We also have a KODI box which was a one time equipment purchase and while it offers access to more recent movies and is no always reliable... so, we don't use it much.
Later in the week, we are going to make another one time equipment purchase for a digital antenna where once connected to our TV, we will be able to watch local channels free-of-charge within a 50-100 mile radius.
Our HULU contract is on a month-to-month basis which is good... but our fiber WIFI is on a 2 year contract which does gives us some concern but something with which we have to live...
BREAK FREE OF CABLE...
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