Treating Obesity

The modified ISD would be non-surgically inserted into the stomach and then pulled back out for each treatment  Adapted from ACS Applied Materials & Interfaces 2022, DOI: 10.1021/acsami.2c00532

While some folks might say that obese people should just exercise more and eat less, things aren't always quite that simple. With that fact in mind, a new implant is being designed to help boost the weight-loss process, by killing hunger-inducing cells in the stomach.

Ghrelin is a naturally produced hormone that stimulates the appetite, increases food intake and promotes the storage of fat. And while small amounts of it are released by the brain, pancreas and small intestine, most of it is produced and secreted by cells in the upper portion of the stomach.

Scientists at the Catholic University of Korea recently set out to reduce the activity of those cells, by modifying an existing prototype implant. Known as the "intragastric satiety-inducing device" (ISD), it consists of a stent which is non-surgically lodged in the lower esophagus, connected to a disc that rests in the opening to the stomach. A small opening in that disc allows food to pass through.

In the new version of the ISD, the underside of the disc is coated with an FDA-approved drug called methylene blue. Additionally, a fiber optic laser passes down through the opening in the disc, curving back around to point at its underside.  READ MORE...

Eye Drops for Blurred Vision

A newly approved eye drop hitting the market on Thursday could change the lives of millions of Americans with age-related blurred near vision, a condition affecting mostly people 40 and older.

Vuity, which was approved by the Food and Drug Administration in October, would potentially replace reading glasses for some of the 128 million Americans who have trouble seeing close-up. The new medicine takes effect in about 15 minutes, with one drop on each eye providing sharper vision for six to 10 hours, according to the company.

Toni Wright, one of the 750 participants in a clinical trial to test the drug, said she liked what she saw.

"It's definitely a life changer," Wright told CBS News national correspondent Jericka Duncan.

Before the trial, the only way Wright could see things clearly was by keeping reading glasses everywhere — in her office, bathroom, kitchen and car.

"I was in denial because to me that was a sign of growing older, you know, needing to wear glasses," she said.

It was in 2019 that her doctor told her about a new eye drop with the potential to correct her vision problems, temporarily. The 54-year-old online retail consultant, who works from her farm in western Pennsylvania, instantly noticed a difference.

"I would not need my readers as much, especially on the computer, where I would always need to have them on," she said.  READ MORE...