Wednesday, April 13
Blood and Mental Disorders
Mental health disorders including depression, schizophrenia, and anorexia show links to biological markers detected in routine blood tests, according to our new study of genetic, biochemical and psychiatric data from almost a million people.
The research will increase our understanding of what causes mental illness and may help to identify new treatments.
Healthy body, healthy mind
People often consider mental health as separate from the health of the rest of the body. This is far from true: there is clear evidence many biochemical substances involved in diseases such as diabetes and autoimmune conditions directly impact the function of our brain.
Many studies have tried to address this by focusing on substances called biomarkers that can be readily measured in blood.
A biomarker is simply something in the body that is a sign of a particular disease or process. These often relate to the kind of things reported in a blood test ordered by your doctor, such as cholesterol, blood sugar, liver enzymes, vitamins, or markers of inflammation.
Biomarkers found in routine blood tests are useful as they are often affected by diet and lifestyle, or by treatment with a drug.
People often consider mental health as separate from the health of the rest of the body. This is far from true: there is clear evidence many biochemical substances involved in diseases such as diabetes and autoimmune conditions directly impact the function of our brain.
Many studies have tried to address this by focusing on substances called biomarkers that can be readily measured in blood.
A biomarker is simply something in the body that is a sign of a particular disease or process. These often relate to the kind of things reported in a blood test ordered by your doctor, such as cholesterol, blood sugar, liver enzymes, vitamins, or markers of inflammation.
Biomarkers found in routine blood tests are useful as they are often affected by diet and lifestyle, or by treatment with a drug.
The complex role of genetics in mental health
It's often difficult to study the role of these blood biomarkers in mental health conditions. Many studies in this area are often not large enough to make strong conclusions.
One solution is to look at genetic influences on both mental illness and substances measured in blood. Genetics is useful as we now have data from millions of individuals who have volunteered in research studies. READ MORE...
It's often difficult to study the role of these blood biomarkers in mental health conditions. Many studies in this area are often not large enough to make strong conclusions.
One solution is to look at genetic influences on both mental illness and substances measured in blood. Genetics is useful as we now have data from millions of individuals who have volunteered in research studies. READ MORE...
Living to 150
Humans could live until the ripe old age of 150 years according to recent research – and scientists are racing to work out how.
Harvard geniuses, biohackers and internet billionaires are all looking for ways that humans can crack the code on aging.
WaitButWhy blogger Tim Urban writes “the human body seems programmed to shut itself down somewhere around the century mark, if it hasn’t already”.
And Urban is right! There are no verified cases of a person living to be older than 122, though the oldest living person is on their way at age 119.
Researchers at GERO.AI concluded the “absolute limit” of the human lifespan to be between 100 and 150 – they came to this conclusion by analyzing 70,000 participants up to age 85 based on their ability to fight disease, risk of heart conditions and cognitive impairment.
The Conversation reported that not a single participant showed the biological resiliency to live to 150 – but notes the study is limited by today’s medical standards.
Will improvements in medicine, environment and technology to drastically lengthen the average lifespan and make 150 a reality?
Humans could live until the age of 150, according to a new study. Shutterstock Brutal biology
The human body is made up of about 30 trillion cells. Cells are constantly dying and being replaced by replicants.
Within the cell body there are chromosomes – these are DNA strands with the code written for humans within them.
At the end of a DNA strand is a microscopic bundle of non-crucial DNA, so that none of the important stuff gets snipped off when the cell divides.
A cell can divide itself about 50 times before it’s lost its ability to replicate.
As more and more cells become ineffective and die, the signs of aging start to show in gray hair, weaker bones and vision loss.
Some theorize this process can be stopped or reversed. READ MORE...
The human body is made up of about 30 trillion cells. Cells are constantly dying and being replaced by replicants.
Within the cell body there are chromosomes – these are DNA strands with the code written for humans within them.
At the end of a DNA strand is a microscopic bundle of non-crucial DNA, so that none of the important stuff gets snipped off when the cell divides.
A cell can divide itself about 50 times before it’s lost its ability to replicate.
As more and more cells become ineffective and die, the signs of aging start to show in gray hair, weaker bones and vision loss.
Some theorize this process can be stopped or reversed. READ MORE...
Tuesday, April 12
Washington DC
Here's an INTERESTING OBSERVATION
1. The sport of choice for the urban poor is BASKETBALL.
2. The sport of choice for maintenance level employees is BOWLING.
3. The sport of choice for front-line workers is FOOTBALL.
4. The sport of choice for supervisors is BASEBALL.
5. The sport of choice for middle management is TENNIS.
And...
6. The sport of choice for corporate executives and officers is GOLF
THE amazing fact is, the more you move up in the hierarchy, the smaller your balls become.
There must be a shit load of people in Washington D C playing marbles...
1. The sport of choice for the urban poor is BASKETBALL.
2. The sport of choice for maintenance level employees is BOWLING.
3. The sport of choice for front-line workers is FOOTBALL.
4. The sport of choice for supervisors is BASEBALL.
5. The sport of choice for middle management is TENNIS.
And...
6. The sport of choice for corporate executives and officers is GOLF
THE amazing fact is, the more you move up in the hierarchy, the smaller your balls become.
There must be a shit load of people in Washington D C playing marbles...
AVARS With Ancient DNA
Reconstruction of an Avar-period armoured horseman based on Grave 1341/1503 of the Derecske-Bikás-dűlÅ‘ site (Déri Museum, Debrecen). Credit: © Ilona C. Kiss
Less known than Attila's Huns, the Avars were their more successful successors. They ruled much of Central and Eastern Europe for almost 250 years. We know that they came from Central Asia in the sixth century CE, but ancient authors as well as modern historians have long debated their provenance.
Now, a multidisciplinary research team of geneticists, archeologists and historians, including researchers from the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, obtained and studied the first ancient genomes from the most important Avar elite sites discovered in contemporary Hungary. This study traces the genetic origin of the Avar elite to a faraway region of East Central Asia. It provides direct genetic evidence for one of the largest and most rapid long-distance migrations in ancient human history.
ila
Now, a multidisciplinary research team of geneticists, archeologists and historians, including researchers from the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, obtained and studied the first ancient genomes from the most important Avar elite sites discovered in contemporary Hungary. This study traces the genetic origin of the Avar elite to a faraway region of East Central Asia. It provides direct genetic evidence for one of the largest and most rapid long-distance migrations in ancient human history.
ila
In the 560s, the Avars established an empire that lasted more than 200 years, centered in the Carpathian Basin. Despite much scholarly debate their initial homeland and origin has remained unclear. They are primarily known from historical sources of their enemies, the Byzantines, who wondered about the origin of the fearsome Avar warriors after their sudden appearance in Europe. Had they come from the Rouran empire in the Mongolian steppe (which had just been destroyed by the Turks), or should one believe the Turks who strongly disputed such a legacy?
Historians have wondered whether that was a well-organized migrant group or a mixed band of fugitives. Archeological research has pointed to many parallels between the Carpathian Basin and Eurasian nomadic artifacts (weapons, vessels, horse harnesses), for instance a lunula-shaped pectoral of gold used as a symbol of power. We also know that the Avars introduced the stirrup in Europe. Yet we have so far not been able to trace their origin in the wide Eurasian steppes. READ MORE...
Hiding in the Lungs
Researchers have discovered a new never-before-seen cell in the human lungs, which plays a vital role in the functioning of the respiratory system. (Image credit: Shutterstock)(opens in new tab)
Scientists have discovered a brand-new type of cell hiding inside the delicate, branching passageways of human lungs. The newfound cells play a vital role in keeping the respiratory system functioning properly and could even inspire new treatments to reverse the effects of certain smoking-related diseases, according to a new study.
The cells, known as respiratory airway secretory (RAS) cells, are found in tiny, branching passages known as bronchioles, which are tipped with alveoli, the teensy air sacs that exchange oxygen and carbon dioxide with the bloodstream. The new RAS cells are similar to stem cells — "blank canvas" cells that can differentiate into any other type of cell in the body — and are capable of repairing damaged alveoli cells and transforming into new ones.
Researchers discovered the RAS cells after becoming increasingly frustrated by the limitations of relying on the lungs of mice as models for the human respiratory system. However, because of certain differences between the two, scientists have struggled to fill some knowledge gaps about human lungs. To get a better understanding of these differences on a cellular level, the team took lung tissue samples from healthy human donors and analyzed the genes within individual cells, which revealed the previously unknown RAS cells. READ MORE...
Scientists have discovered a brand-new type of cell hiding inside the delicate, branching passageways of human lungs. The newfound cells play a vital role in keeping the respiratory system functioning properly and could even inspire new treatments to reverse the effects of certain smoking-related diseases, according to a new study.
The cells, known as respiratory airway secretory (RAS) cells, are found in tiny, branching passages known as bronchioles, which are tipped with alveoli, the teensy air sacs that exchange oxygen and carbon dioxide with the bloodstream. The new RAS cells are similar to stem cells — "blank canvas" cells that can differentiate into any other type of cell in the body — and are capable of repairing damaged alveoli cells and transforming into new ones.
Researchers discovered the RAS cells after becoming increasingly frustrated by the limitations of relying on the lungs of mice as models for the human respiratory system. However, because of certain differences between the two, scientists have struggled to fill some knowledge gaps about human lungs. To get a better understanding of these differences on a cellular level, the team took lung tissue samples from healthy human donors and analyzed the genes within individual cells, which revealed the previously unknown RAS cells. READ MORE...
4 Day Workweek
KNOXVILLE, Tenn. (WATE) — Not everyone is an expert in human resources or business management and there are terms used among professionals in these industries that could be useful to others whom are employed; emerging data on the four-day workweek calls attention to some terms used among management experts and the history of the American workweek.
Academics and business industry professionals are talking more about the four-day workweek and discussions have been happening for years. Tim Munyon, associate professor of management at UT Haslam College of Business, offered both a history lesson on the topic as well as what some of the terms used actually mean. Munyon also touched on some recent studies and academic literature aimed at not only employee productivity but also the historical effects.
Recently, the shortened American workweek became a trending topic among international media and on social media when a study out of Iceland called the four-day workweek a success and a California congressman introduced legislation to modify the workweek last summer that was endorsed by the Congressional Progressive Caucus in December.
Academics and business industry professionals are talking more about the four-day workweek and discussions have been happening for years. Tim Munyon, associate professor of management at UT Haslam College of Business, offered both a history lesson on the topic as well as what some of the terms used actually mean. Munyon also touched on some recent studies and academic literature aimed at not only employee productivity but also the historical effects.
Recently, the shortened American workweek became a trending topic among international media and on social media when a study out of Iceland called the four-day workweek a success and a California congressman introduced legislation to modify the workweek last summer that was endorsed by the Congressional Progressive Caucus in December.
Terms defined
Business researchers are finding that more companies are considering or switching to a results-only work environment, or ROWE that focuses on complete autonomy and accountability for outcomes only.
A broader approach to ROWE some companies are taking includes flexible work practices or FWP, which have seen positive effects according to research prior to the coronavirus pandemic – and after – but meta-analyses (“studies of studies, as Munyon put it) on these practices are still being developed that aim to reduce or and bias.
A peer-reviewed business research study published in late 2017 explored the different avenues of FWP and how companies attract potential employees – and keep them – utilizing FWPs. Overall, FWPs produce positive results, according to the meta-analyses, and Munyon summarizes this when asked about FWPs and ROWEs. READ MORE...
Business researchers are finding that more companies are considering or switching to a results-only work environment, or ROWE that focuses on complete autonomy and accountability for outcomes only.
A broader approach to ROWE some companies are taking includes flexible work practices or FWP, which have seen positive effects according to research prior to the coronavirus pandemic – and after – but meta-analyses (“studies of studies, as Munyon put it) on these practices are still being developed that aim to reduce or and bias.
A peer-reviewed business research study published in late 2017 explored the different avenues of FWP and how companies attract potential employees – and keep them – utilizing FWPs. Overall, FWPs produce positive results, according to the meta-analyses, and Munyon summarizes this when asked about FWPs and ROWEs. READ MORE...
Monday, April 11
Boosting the Immune System
Understanding which vitamins boost the immune system is imperative. After all, our world is not sterile. Every day, we are exposed to a myriad of harmful microbes that are constantly evolving to get better at infecting us.
Knowing the risks, we often try to do everything in our power to protect ourselves from falling ill. We might put on a jacket, drink some hot tea and head to a pharmacy for some reinforcements.
But do we know which vitamins boost the immune system? And is it even possible to fight off a cold with certain nutrients, or is it just a marketing gimmick?
It’s hard to understate the role that nutrition plays in maintaining our health and wellbeing. Studies(opens in new tab) have shown that a diet that consists mostly of wholefoods and provides a sufficient amount of good quality protein (our guide to the best protein powder can help if you’re struggling to meet your intake) is key to longevity and improved quality of life.
It’s hard to understate the role that nutrition plays in maintaining our health and wellbeing. Studies(opens in new tab) have shown that a diet that consists mostly of wholefoods and provides a sufficient amount of good quality protein (our guide to the best protein powder can help if you’re struggling to meet your intake) is key to longevity and improved quality of life.
However, our immune system is arguably the most complex part of the human body apart from the brain and it may require more than getting few specific nutrients to keep it in peak condition.
Here, we’ll look at whether vitamins can really boost the immune system and which of these nutrients are important for helping you to stay healthy. READ MORE...
Here, we’ll look at whether vitamins can really boost the immune system and which of these nutrients are important for helping you to stay healthy. READ MORE...
Powerful Space Laser
Powerful, radio-wavelength laser light has been detected emanating from the greatest distance across deep space yet.
It's a type of massless cosmic object called a megamaser, and its light has traveled for a jaw-dropping 5 billion light-years to reach us here on Earth. The astronomers who discovered it using the MeerKAT radio telescope in South Africa have named it Nkalakatha – an isiZulu word meaning "big boss".
The discovery has been accepted into The Astrophysical Journal Letters and is available on preprint server arXiv.
"It's impressive that, with just a single night of observations, we've already found a record-breaking megamaser," said astronomer Marcin Glowacki of the Curtin University node of the International Centre for Radio Astronomy Research (ICRAR) in Australia.
"It shows just how good the telescope is."
A maser is the microwave equivalent of a laser (light amplification by stimulated emission of radiation). Rather than emitting visible light, a maser emits microwave and radio wavelengths that are stimulated and amplified. For an astrophysical maser, the processes that amplify the light are cosmic; planets, comets, clouds, and stars can all produce masers.
As you may have guessed it, a megamaser is therefore a maser with some serious oomph. Generally these emissions are produced by an object that is going absolutely ham in some way; for instance, active supermassive black holes can produce megamasers.
When the data came in from the first night of a survey planned for 3,000 hours, Glowacki and team found the signature of a very specific type of megamaser, bright in wavelengths amplified by stimulated hydroxyl molecules, consisting of one hydrogen atom and one oxygen atom. READ MORE...
Communicating Fungi
A new study has identified patterns of nerve-like electrical activity being produced by fungi. What's more, patterns within the activity appear to be comparable to similar structures in humans speech.
Assuming the impulses might be influencing other cellular activities in a network of fungi, it's a finding that could shed new light on communication in mycological organisms.
Computer scientist Andrew Adamatzky, from the University of the West of England in the UK, was able to spot up to 50 different 'words' or groups of spikes of activity produced by the fungi networks that were studied.
Electrical buzzes in fungi have been known about for years, but analyzing this activity as if it were a language could stand to reveal many things we don't know about what this fungi phenomena represents.
"Assuming that spikes of electrical activity are used by fungi to communicate and process information in mycelium networks, we group spikes into words and provide a linguistic and information complexity analysis of the fungal spiking activity," writes Adamatzky in his new paper.
Caterpillar fungi being analyzed. (Andy Adamatzky)
Adamatzky looked at electrical activity across four types of fungi, looking for patterns in ghost fungi (Omphalotus nidiformis), Enoki fungi (Flammulina velutipes), split gill fungi (Schizophyllum commune), and caterpillar fungi (Cordyceps militaris).
Electrical activity was detected and recorded using tiny microelectrodes inserted across areas where the fungi had colonized, and spikes in activity were then organized into groups. Each type of fungi varied in terms of its spike duration and length, with some spikes lasting up to 21 hours. READ MORE...
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